Genetic engineering to hide donor organs from the host's immune system is an advanced biotechnological approach aimed at reducing organ transplant rejection. The immune system naturally identifies and attacks foreign tissues, which can lead to transplant rejection. Through genetic engineering, scientists modify the donor organ at a cellular level to make its tissue appear more like the host's own cells. This is achieved by altering specific genes responsible for the antigens that trigger an immune response. Techniques like CRISPR-Cas9 are often employed to edit these genes precisely. By camouflaging the donor organ or reducing its immunogenic profile, this technology significantly increases the success rates of transplants and may decrease the need for immunosuppressive drugs that come with severe side effects. This innovation holds great promise in enhancing transplant outcomes and improving the quality of life for recipients.
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